(+)-Alfa-barbatenska sintaza
| (+)-Alfa-barbatenska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.69 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz unos | ||||||||
| BRENDA | BRENDA unos | ||||||||
| ExPASy | NiceZyme unos | ||||||||
| KEGG | KEGG unos | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profil | ||||||||
| PDB struktura | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
(+)-Alfa-barbatenska sintaza (EC 4.2.3.69, AtBS) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (formira (+)-alfa-barbaten).[1][2] Ovaj enzim katalizira sljedeću kemijsku reakciju
- (2E,6E)-farnezil difosfat (+)-alfa-barbaten + difosfat
Rekombinirajući enzim iz biljke Arabidopsis thaliana formira 27.3% alfa-barbatena, 17.8% tujopsena i 9.9% beta-hamigrena.
Izvori[uredi | uredi kôd]
- ↑ Wu, S., Schoenbeck, M.A., Greenhagen, B.T., Takahashi, S., Lee, S., Coates, R.M. and Chappell, J. 2005. Surrogate splicing for functional analysis of sesquiterpene synthase genes. Plant Physiol. 138: 1322–1333. PMID 15965019CS1 održavanje: više imena: authors list (link)
- ↑ Tholl, D., Chen, F., Petri, J., Gershenzon, J. and Pichersky, E. 2005. Two sesquiterpene synthases are responsible for the complex mixture of sesquiterpenes emitted from Arabidopsis flowers. Plant J. 42: 757–771. PMID 15918888CS1 održavanje: više imena: authors list (link)
Literatura[uredi | uredi kôd]
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- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems Book 44 izdanje. Wiley Classics Library. ISBN 0471303097
- Robert A. Copeland. 2013. Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists 2nd izdanje. Wiley-Interscience. ISBN 111848813X
- Gerhard Michal, Dietmar Schomburg. 2012. Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology 2nd izdanje. Wiley. ISBN 0470146842