Betakoronavirus 1

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Betakoronavirus 1 je vrsta koronavirusa koja inficira ljude i stoku. Virus koji inficira je jednolančani RNK virus, s pozitivnim osjećajem, i pripadnik je roda Betakoronavirus i subgena Embecovirus.[1] Kao i ostali embekovirusi ima dodatni kraći površinski protein u obliku šiljka, nazvan hemaglutinin esteraza (HE).[2][3]

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  1. Taxonomy browser (Betacoronavirus 1). www.ncbi.nlm.nih.gov. Pristupljeno 29. veljače 2020.
  2. Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung. 24. kolovoza 2010. Coronavirus Genomics and Bioinformatics Analysis. Viruses. 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. In all members of Betacoronavirus subgroup A, a haemagglutinin esterase (HE) gene, which encodes a glycoprotein with neuraminate O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1).
  3. Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung. 24. kolovoza 2010. Coronavirus Genomics and Bioinformatics Analysis. Viruses. 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus.